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Synovial monocytes contribute to chronic inflammation in childhood-onset arthritis via IL-6/STAT signalling and cell-cell interactions

Synovial monocytes from untreated oligoarticular juvenile idiopathic arthritis patients were investigated to understand their role in chronic inflammation. These monocytes displayed increased T‑cell activation, resistance to cytokine production after …

Identification of novel autoantigens as potential biomarkers in juvenile idiopathic arthritis associated uveitis

This study sought to identify autoantigens associated with uveitis in ANA‑positive oligoarticular juvenile idiopathic arthritis (JIA). Antibodies from patients with and without uveitis were analysed using peptide arrays and immunoprecipitation …

Psychometric properties of the Persian version of the overall anxiety severity and impairment scale (OASIS)

Objectives: This study was conducted to assess the psychometric properties of the Persian version of the overall anxiety severity and impairment scale (OASIS), a measure designed to evaluate the severity and functional impairments associated with …

A Von Mises-Fisher clustering modeling for the inference of orientational preferences of protein domains with scattering data

This conference abstract describes a directional probabilistic model to infer the orientational preferences of protein domains from small‑angle X‑ray scattering (SAXS) data. Two beads connected by a thread represent a flexible protein linker; the …

Sleep abnormalities in individuals at clinical high risk for psychosis

Youth at clinical high risk (CHR) represent a unique population enriched for precursors of major psychiatric disorders. Sleep disturbances are consistently reported in CHR individuals. However, there is a dearth of studies investigating quantifiable …

On the Extended Chen Distribution: Development, Properties, Characterizations and Applications

In this paper, a flexible model called extended Chen (EC) distribution is derived from the generalized Burr-Hatke differential equation and nexus between the exponential and gamma variables. The EC distribution is also derived from compounding …

Cubic Rank Transmuted Modified Burr III Distribution: Development, Properties, Characterizations and Applications

Functional singular spectrum analysis

In this paper, we develop a new extension of the singular spectrum analysis (SSA) called functionalSSA to analyze functional time series. The new methodology is constructed by integrating ideasfrom functional data analysis and univariate SSA. …

Functional brain response to emotional musical stimuli in depression, using INLA approach for approximate Bayesian inference

Introduction: One of the vital skills which has an impact on emotional health and well-being is the regulation of emotions. In recent years, the neural basis of this process has been considered widely. One of the powerful tools for eliciting and …

Functional singular spectrum analysis

This article introduces functional singular spectrum analysis (FSSA), an extension of singular spectrum analysis for functional time series. By defining a functional trajectory operator and developing a computationally tractable functional singular …