Cerebrospinal Fluid

Data-Driven Cluster Analysis of Cerebrospinal Fluid Proteome and Associations with Clinical Phenotypes in Systemic Lupus Erythematosus

OBJECTIVE: To explore the cerebrospinal fluid (CSF) proteome in systemic lupus erythematosus (SLE) and the associations between the CSF proteomic patterns and clinical manifestations. CSF samples from 29 female outpatients with SLE were analysed …

Data-driven clustering of cerebrospinal fluid proteome reflects clinical phenotypes of systemic lupus erythematosus

Objective: Neuropsychiatric (NP) manifestations are common in systemic lupus erythematosus (SLE). Because cerebrospinal fluid (CSF) protein patterns may provide insight into NP pathogenesis, this study used a data‑driven approach to determine whether …