Juvenile Idiopathic Arthritis

Synovial monocytes contribute to chronic inflammation in childhood-onset arthritis via IL-6/STAT signalling and cell-cell interactions

Synovial monocytes from untreated oligoarticular juvenile idiopathic arthritis patients were investigated to understand their role in chronic inflammation. These monocytes displayed increased T‑cell activation, resistance to cytokine production after …

Identification of novel autoantigens as potential biomarkers in juvenile idiopathic arthritis associated uveitis

This study sought to identify autoantigens associated with uveitis in ANA‑positive oligoarticular juvenile idiopathic arthritis (JIA). Antibodies from patients with and without uveitis were analysed using peptide arrays and immunoprecipitation …