Systemic Lupus Erythematosus

Endothelial dysfunction, arterial stiffness, and neuronal injury in systemic lupus erythematosus: associations with type I interferon

Objectives: To examine how type I interferon (IFN-α) relates to vascular and neuronal abnormalities in systemic lupus erythematosus (SLE) and whether vascular dysfunction correlates with neuronal injury. Methods: In this cross‑sectional study of 147 …

Data-Driven Cluster Analysis of Cerebrospinal Fluid Proteome and Associations with Clinical Phenotypes in Systemic Lupus Erythematosus

OBJECTIVE: To explore the cerebrospinal fluid (CSF) proteome in systemic lupus erythematosus (SLE) and the associations between the CSF proteomic patterns and clinical manifestations. CSF samples from 29 female outpatients with SLE were analysed …

Data-driven clustering of cerebrospinal fluid proteome reflects clinical phenotypes of systemic lupus erythematosus

Objective: Neuropsychiatric (NP) manifestations are common in systemic lupus erythematosus (SLE). Because cerebrospinal fluid (CSF) protein patterns may provide insight into NP pathogenesis, this study used a data‑driven approach to determine whether …